1) As a broad spectrum anti-microbial mimosa demonstrates effectiveness against Aspergillus fumigatus, Citrobacter divergens, Plasmodium berghei, and Klebsiella pneumonia in studies (6). Clinically, physicians have reported it to be effective in treating various parasites as well as various forms of Borrelia (14). According to a few physicians that have used mimosa for a number of years “many patients experience elimination of parasites into the toilet so they have to be informed prior to starting the herb” that visible parasites are a possibility (14).
2) Mimosa is the go to herb for Hemorrhoids in Ayurveda. This is due to the amazing wound healing abilities of the methanolic extracts of the plant. Traditionally the powder has been made into a paste and applied topically but oral supplementation can be effective as well.
3) Anti-diarrheal activity was demonstrated on rats that were given castor oil induced diarrhea and PGE2 induced enteropooling along with reducing gut motility after a charcoal meal. The ethanolic extract of Mimosa showed significant diarrhea inhibition (7).
4) Anti hepatotoxic activity was demonstrated through the measurement of high serum SGOT, SGPT, ALP, and total bilirubin in CCL4 induced liver damage in albino rats. Mimosa helped achieve near normal levels within 14 days (3).
5) Anti-diabetic activity was demonstrated in a study with rats on a high fructose diet. Mimosa reduced the body weight, improved insulin sensitivity, lowered blood lipids and reduced liver damage. Furthermore, blood tests showed in a different study that serum cholesterol, triglycerides, LDL, and VLDL all decreased while HDL increased (10).
6) Analgesic and anti-inflammatory activity has been demonstrated due to the flavonoid presence in the ethanolic extract.
7) Mimosa demonstrated potent anti-venom activity. This was demonstrated by the inhibition of lethality, phospholipase activity, edema forming activity, fibrinolytic activity and hemorrhagic activity of Naja naja and Bangarus caerulus venoms (4).
8) Anti-ulcer activity was demonstrated against pylorus ligation, aspirin and ethanol-induced ulcers due to the plants ethanolic extract (11).
9) Mimosa does possess anti-convulsant activity, specifically for drug-induced seizures. It also demonstrated to be an antagonist for N-methyl-D-aspartate induced turning behavior (13).
To quote Fagenholz: “In conclusion, Mimosa possesses great medicinal properties. It seems to benefit the majority of patients with microbial issues. However, we do view it as an elite anti-parasitic due to its action on large intestinal worms. This herb needs to be considered in any resistant parasitic or microbial patient cases and in all patients that test positive for Borrelia” (14).
Mimosa Pudica is listed as a non-toxic plant for humans on the University of California's list of safe and poisonous garden plants (15). It is also listed as safe for humans and pets on the University of Connecticut College of Agriculture and Natural Resources website.
Dosage: The dosage is 2 capsules in the morning and 2 before bed on an empty stomach ideally. Some sensitive patients may experience discomfort and need to start at a lower does. However, we have had some of the most sensitive patients not have any discomfort at all so we advise to just monitor your patients.
Contraindications: Mimosa should not be taken during pregnancy or while nursing or in children under 6. As with other supplements children’s dosage should be determined by weight.
1. Ahmad H, Sehgal S, Mishra A, Gupta R. Mimosa pudica L. (Laajvanti): An overview. Pharmacogn Rev. 2012 Jul;6(12):115-24. doi: 10.4103/0973-7847.99945.
2. Kokane DD, More RY, Kale MB, Nehete MN, Mehendale PC, Gadgoli CH. Evaluation of wound healing activity of root of Mimosa pudica. J Ethnopharmacol. 2009 Jul 15;124(2):311-5. doi: 10.1016/j.jep.2009.04.038. Epub 2009 May 3.
3. Muthukumaran P, Pattabiraman K, Kalaiyarasan P. Hepato protective and antioxidant activity of mimosa pudica on carbon tetra chloride-induced hepatic damage in rats. International Journal of Current Research 2010; 10:046-053.
4. Meenatchisundaram S, Priyagrace S, Vijayaraghavan R, Velmurugan A, Parameswari G, Michael A. Antitoxin activity of Mimosa pudica root extracts against Naja naja and Bangarus caerulus venoms. Bangladesh J Pharmacol. 2009; 4: 105-109.
5. Elango V, Carolin Oliver1 Raghu PS. Antiulcer activity of the Leaf ethanolic extract of Mimosa pudica in Rats. Hygeia. J. D. Med. 2012; 4 (1): 34-40.
6. Gandhiraja N, Sriram S, Meena V, Srilakshmi K, Sasikumar C, Rajeshwari R. Phytochemical Screening And Antimicrobial Activity of the Plant Extracts of Mimosa pudica L. Against Selected Microbes. Ethnobotanical Leaflets 2009; 13:618-24.
7. Saifiddin Khalid MD, Jinesh kumar S, Suresh DK, Kumar R. Evaluation of an anti-diarrhoeal potential of ethanolic extract of mimosapudica leaves. IJGP 2011; 5(1): 75-78.
8. Bendgude RD, Maniyar1 MG, Kondawar MS, Patil SB, Hirave RV. Anthelmintic Activity of Leaves of Mimosa pudica. International Journal of Institutional Pharmacy and life sciences 2012; 2(!).
9. Aarthi N, Murugan K. Antimalarial activity and phytochemical screening of ethanolic leaf extract of phyllanthus niruri and mimosa pudica. IJPRD 2011; 3(3)24: 198 205.
10. Rajendran R, Krishnakumar E. Hypolipidemic Activity of Chloroform Extract of Mimosa pudica Leaves. Avicenna J Med Biotech. 2010; 2(4): 215-221.
11. Elango V, Carolin Oliver1 Raghu PS. Antiulcer activity of the Leaf ethanolic extract of Mimosa pudica in Rats. Hygeia. J. D. Med. 2012; 4 (1): 34-40.
12. Joseph, Baby, Jency George, and Jeevitha Mohan. "Pharmacology and Traditional Uses of Mimosa Pudica." International Journal of Pharmaceutical Sciences and Drug Research 5.2 (2013): 41-44. Web.
13. Ngo Bum E, Dawack DL, Schmutz M, Rakotonirina A, Rakotonirina SV, Portet C, Jeker A, Olpe HR, Herrling P. Anticonvulsant activity of Mimosa pudica decoction. Fitoterapia 2004; 75 (3-4):309-14.
14. Charles Fagenholz DC- private conversations
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